MeSH ID: 68011506
Proteins are linear polypeptides that are synthesized on ribosomes and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of amino acids determines the shape the polypeptide will take, during protein folding, and the function of the protein.
Best practice for sharing this type of data:
Refer to the minimum information about a proteomics experiment (MIAPE) reporting guidelines for an outline of the materials that should be presented along with all relevant datasets.
Most suitable repositories:
Protein data may be added to repositories such as BindingDB of measured binding affinities, Biological General Repository for Interaction Datasets, Database of Interacting Proteins, NCBI Protein Clusters, FlyBase, NCBI Identical Protein Groups, Gene Ontology Annotation Database, Innate DB, IntAct molecular interaction database, Interologous Interaction Database, Life Science Database Archive, MatrixDB: Extracellular Matrix Interaction Database, MEROPS, PeptideAtlas, Pfam, GlycoProtDB, UniCarb-DR, Glycans, PRIDE, PRINTS, PROSITE, PCDDB, Protein Data Bank in Europe, Protein Data Bank of Japan, Pubchem, RCSB Protein Data Bank, Signaling Pathways Project, STRENDA DB, Structural Biology Data Grid, The Global Proteome Machine Database, The Protein Database, UniProt Knowledgebase, VectorBase, and Worldwide Protein Data Bank.
Best practice for indicating re-use of existing data:
For public datasets please provide a DOI or other stable identified for the dataset itself *and* include a citation for the dataset in the reference list. Be sure to indicate exactly which data has been re-used, particularly when multiple versions of the dataset exist. In many cases, this is best achieved by sharing the code used to extract the part of the data that you analyzed. In some cases it may be best to share the exact dataset(s) you analyzed as well.
For access-controlled data authors should provide a link to instructions for obtaining access (e.g. here is the information page for ADNI (Alzheimer's Disease Neuroimaging Initiative): http://adni.loni.usc.edu/data-samples/access-data/).
When re-using a private dataset from a previous study please contact the data owners to discuss how the data can be made public.