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Genetic Data- Restriction Fragment Length Polymorphism

MeSH ID: D012150

Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.

Best practice for sharing this type of data:
When possible the original data output should be shared (e.g. the Electrophoresis or sequencer output file). The scored genotypes should be shared as Tabular data, ensuring that the names for individual samples are consistent with those used in the article and in other related datasets. Tabular data should saved as a .txt or .csv file. The first row(s) should contain information about the dataset, such as the data file name, author, today's date, when the data within the file were last modified, and companion file names. Please also state which symbol has been used to denote missing data (NA is preferred). Column headings should describe the content of each column and contain only numbers, letters, and underscores - no spaces or special characters. Lowercase letters are preferred. Row names should be consistent with those used in the article and in other related datasets.

Most suitable repositories:
RFLP data may be added to European Variation Archive, NCBI Genome, Genetic Testing Registry, Reference Sequence Database, NCBI Gene, and Database of Genomic Structural Variation

Best practice for indicating re-use of existing data:
For public datasets please provide a DOI or other stable identified for the dataset itself *and* include a citation for the dataset in the reference list. Be sure to indicate exactly which data has been re-used, particularly when multiple versions of the dataset exist. In many cases, this is best achieved by sharing the code used to extract the part of the data that you analyzed. In some cases it may be best to share the exact dataset(s) you analyzed as well.

For access-controlled data authors should provide a link to instructions for obtaining access (e.g. here is the information page for ADNI (Alzheimer's Disease Neuroimaging Initiative):

When re-using a private dataset from a previous study please contact the data owners to discuss how the data can be made public.

data_type/genetic_data/restriction_fragment_length_polymorphism.txt · Last modified: 2022/07/08 05:33 by souad